Which drugs have negotiated prices in 2027?
| Drug | Commonly used to treat | 2027 negotiated price | 2024 list price | Lower by |
|---|---|---|---|---|
| Ozempic, Rybelsus, Wegovy | Type 2 diabetes, heart disease, and obesity or overweight | $274 | $959 | 71% |
| Trelegy Ellipta | Asthma and COPD | $175 | $654 | 73% |
| Xtandi | Prostate cancer | $7,004 | $13,480 | 48% |
| Pomalyst | Multiple myeloma and Kaposi sarcoma | $8,650 | $21,744 | 60% |
| Ofev | Idiopathic pulmonary fibrosis | $6,350 | $12,622 | 50% |
| Ibrance | Breast cancer | $7,871 | $15,741 | 50% |
| Linzess | Chronic constipation and IBS with constipation | $136 | $539 | 75% |
| Calquence | Chronic lymphocytic leukemia, small lymphocytic lymphoma and mantle cell lymphoma | $8,600 | $14,228 | 40% |
| Austedo, Austedo XR | Chorea from Huntington's disease and tardive dyskinesia | $4,093 | $6,623 | 38% |
| Breo Ellipta | Asthma and COPD | $67 | $397 | 83% |
| Xifaxan | Hepatic encephalopathy and IBS with diarrhea | $1,000 | $2,696 | 63% |
| Vraylar | Bipolar I disorder, major depression and schizophrenia | $770 | $1,376 | 44% |
| Tradjenta | Type 2 diabetes | $78 | $488 | 84% |
| Janumet, Janumet XR | Type 2 diabetes | $80 | $526 | 85% |
| Otezla, Otezla XR | Psoriasis, psoriatic arthritis and mouth ulcers from Behçet's disease | $1,650 | $4,722 | 65% |
COPD is chronic obstructive pulmonary disease, and IBS is irritable bowel syndrome. The list price is the drug company's wholesale price before rebates and discounts.
Will I pay less at the pharmacy?
It depends on your plan. The negotiated price is the price of the drug itself, not your copay. If you pay a percentage of the drug's price, for example while you meet your deductible or when your plan charges coinsurance, a lower price lowers your share. If you pay a flat copay, your cost may not change.
CMS estimates the new prices will save people with Medicare about $685 million out of pocket in 2027. About 5.3 million people with Part D used these drugs in 2024. Part D also caps what you pay for covered drugs at $2,400 in 2027.
Which drugs already have negotiated prices?
The first 10 negotiated prices started January 1, 2026: Eliquis, Jardiance, Xarelto, Januvia, Farxiga, Entresto, Enbrel, Imbruvica, Stelara, and Fiasp and NovoLog insulin. With the 15 new drugs, 25 drugs have negotiated prices in 2027. Prices from the next round take effect in 2028.
What should I do during Medicare open enrollment?
Medicare's Annual Enrollment Period runs October 15 to December 7, 2026. Check that each plan you compare covers your drugs, see which tier they are on and compare the total yearly cost, not just the premium. Every Medicare drug plan must include the negotiated drugs on its drug list, but what you pay for them still differs from plan to plan.
A licensed agent can compare plans using your exact drug list, at no cost to you.
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